Dual Transversus Abdominis Plane Block in Pediatric Renal Transplant: Effect on Pain Control

Cairo University (CU)

Status: Completed

Conditions: Renal Failure

Treatments: Drug: fentanyl; Drug: bupivacaine; Drug: perfalgan; Drug: Pethidine

Study type: Interventional

Funder types: Other

Identifiers

NCT02858622

SMS2016-1

Details and patient eligibility

About

Alleviating pain in children undergoing renal transplant is extremely challenging. Large incisions as those of renal transplant (Gibson's incision) require special techniques of pain control that don't affect hemodynamics or renal function. Since the transplant incision doesn't cross midline; a dual-TAP block is thought to be effective in providing pain control in such procedure as it will anesthetize the dermatomes T6-T12, the muscles of the anterior abdominal wall together with the underlying parietal peritoneum.

Enrollment: 44 patients

Sex: All

Ages: 3 to 16 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 3-16 years
• end stage renal disease
• no known allergy to bupivacaine
• both sexes

Exclusion criteria

• known allergy to bupivacaine

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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44 participants in 2 patient groups

dual TAB group

Active Comparator group

Description:

22 patients will receive unilateral dual transversus abdominis plane (TAB) block USING bupivacaine 0.25% at a dose of 2 mg/kg

Treatment:

Drug: perfalgan

Drug: bupivacaine

Drug: Pethidine

Drug: fentanyl

control group

Sham Comparator group

Description:

22 patients who will not receive dual TAB block

Treatment:

Drug: perfalgan

Drug: Pethidine

Drug: fentanyl