Duloxetine on Bone Metabolism

Çukurova University

Status: Enrolling

Conditions: Fibromyalgia; Chronic Pain

Treatments: Drug: Duloxetine

Study type: Observational

Funder types: Other

Identifiers

NCT05550506

Duloxetine on Bone Metabolism

Details and patient eligibility

About

The aim of the study was to determine the effect of duloxetine as monotherapy on biochemical markers and bone mineral density.

Full description

51 patients diagnosed with chronic pain or fibromyalgia syndrome who were using duloxetine for at least 3 months and age and sex matched 51 healthy individuals were recruited for this cross-sectional study. Bone mineral density of both groups were measured by dual energy x ray absorbsiometry(DXA), bone biochemical markers, serum calcium, and vitamin D levels were investigated.

Enrollment: 102 estimated patients

Sex: All

Ages: 18 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• >18 years or <50 years
• patients using duloxetine for at least 3 months due to chronic pain or fibromyalgia

Exclusion criteria

• postmenopausal women
• clinical conditions which cause secondary osteoporosis
• patients using medication that cause secondary osteoporosis
• pregnancy and malignity

Trial design

102 participants in 2 patient groups

Duloxetine Group

Description:

Patients who use duloxetine at least 3 months for chronic pain or fibromyalgia

Treatment:

Drug: Duloxetine

Healthy Group

Description:

Age and sex matched 51 healthy individuals