Duplex Ultrasound Versus Conventional Angiography in Evaluating Lower Limb Threatening Ischemia (DUS-CTA)

Sohag University

Status: Not yet enrolling

Conditions: Chronic Threatening Lower Limb Ischemia

Treatments: Radiation: conventional angiography

Study type: Interventional

Funder types: Other

Identifiers

NCT07113197

Soh-Med-25-7-22MS

Details and patient eligibility

About

This study aims to evaluate the accuracy of Duplex Ultrasound (DUS) in assessing infra inguinal arterial lesions in patients with chronic threatening limb ischemia compared with digital subtraction angiography (DSA) as the reference standard. By comparing sensitivity, specificity, and predictive values across arterial segments, the study seeks to determine the clinical utility of DUS as a non-invasive alternative for pre-intervention vascular mapping in chronic limb-threatening ischemia.

Enrollment: 50 estimated patients

Sex: All

Ages: 40+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 1. Clinical diagnosis of chronic threatening lower limb ischemia (rest pain, non-healing ulcer, or gangrene).

2. Ability to provide informed consent.

Exclusion criteria

• 1. Hemodynamically unstable patients not fit for angiography. 2. Patients with non-atherosclerotic arterial diseases (e.g., vasculitis, Buerger's disease).

  2. Known contrast allergy or renal insufficiency precluding contrast angiography.

  3. Inadequate acoustic window or inability to undergo complete DUS examination.

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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50 participants in 1 patient group

patients with chronic threatening limb ischemia

Experimental group

Description:

Duplex Ultrasound (DUS) assessment of infra inguinal arterial lesions in patients with chronic threatening limb ischemia and then compared with digital subtraction angiography (DSA) as the reference standard.

Treatment:

Radiation: conventional angiography