Durability at 20 Years of Quadrangular Resection With Annular Plication for Mitral Regurgitation

Michele De Bonis

Status: Completed

Conditions: Mitral Valve Disease

Treatments: Procedure: Quadrangular resection and annular plication

Study type: Observational

Funder types: Other

Identifiers

NCT05724537

DURQUAP 2017

Details and patient eligibility

About

Degenerative mitral regurgitation (MR) due to prolapse of the posterior leaflet is the most common dysfunction of the mitral valve (MV) in the Western world and is nowadays treated with a variety of surgical techniques. Quadrangular resection combined with annular plication and annuloplasty, as originally described by Carpentier, has been the standard approach for many years, before sliding/folding plasty and artificial chordae gained larger popularity.However, very few studies have been published on thevery long-term results (up to 20 years) of quadrangular resection and annular plication, often reporting only freedom from reoperation rather than from recurrent MR. This study aims to evaluate the very long-term (20 years) clinical and echocardiographic results of this approach, which was used for many years at the beginning of our mitral repair program.

Enrollment: 145 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult patients
• Affected by mitral valve posterior leaflet prolapse/flail causing severe mitral regurgitation
• Treated with quadrangular resection of the posterior leaflet and annulus plication

Exclusion criteria

• Other patients