Dynamic Contrast Enhancement Computed Tomography Based Technic to Assess Gastro Intestinal Wall Perfusion : Feasibility Study (PERFE-CT)

Poitiers University Hospital

Status: Completed

Conditions: Mesenteric Ischemia; Permeability CT Technics

Treatments: Radiation: Dynamic contrast enhanced computerised tomography

Study type: Interventional

Funder types: Other

Identifiers

NCT03367065

PERFE-CT

Details and patient eligibility

About

This feasibility study has therefore several aims:

1. construct a dedicated CT perfusion protocol for GIT wall perfusion;
2. used a two-compartment pharmacokinetic model which is more adapted that a unique compartment model;
3. from the image acquired, evaluate current parameters of perfusion including the permeability ones

Enrollment: 10 patients

Sex: All

Ages: 50+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• all patients over fifty years old with clinico-biological suspicion for acute GITischemia admitted at our institution

Exclusion criteria

• contra-indication to contrast agent injection as so defined by the European Society of UroRadiology in 2014
• inability to provide informed consent

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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10 participants in 1 patient group

Dynamic contrast enhanced computerised tomography

Experimental group

Treatment:

Radiation: Dynamic contrast enhanced computerised tomography