Dynamic Myocardial Perfusion Imaging by 320 Multidetector Computed Tomography

University of Edinburgh

Status: Completed

Conditions: Coronary Heart Disease

Treatments: Radiation: Computed tomography scan

Study type: Observational

Funder types: Other

Identifiers

NCT01368237

210/R/CAR/11

Details and patient eligibility

About

Recent advances in technology have resulted in the development of scanners that can image the heart blood vessels within 10 to 20 minutes but without the need for admission to hospital or insertion of catheters. Further advances in technology allow the visualisation of both the blood vessels and the supply of blood to the heart muscle. Here we propose to assess the latest and most powerful computed tomography scanner and compare it to magnetic resonance and conventional coronary angiography.

Enrollment: 51 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• referred for invasive coronary angiography because of suspected coronary heart disease

Exclusion criteria

• inability or unwillingness to undergo computed tomography or magnetic resonance imaging
• renal failure (serum creatinine >200 micromol/L or estimated glomerular filtration rate <30 mL/min)
• hepatic failure
• allergy to iodinated contrast or gadolinium
• pregnancy
• contraindication to adenosine infusion
• inability to give informed consent
• inability to perform fractional flow reserve during invasive coronary angiography

Trial design

51 participants in 1 patient group

Patients

Description:

Patients awaiting invasive coronary angiography

Treatment:

Radiation: Computed tomography scan