Dynamic Thoracic Impedance as a Marker for Heart Failure Decompensation

Charles Porter, MD

Status: Completed

Conditions: Heart Failure; With Decompensation

Treatments: Device: Medtronic ICDs, CRT-Ds, and CRT-Ps

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT02134379

STUDY00000596

Details and patient eligibility

About

This pilot study proposes to perform measurements of approved thoracic impedance technology that will help answer questions in patients with decompensated heart failure.

Full description

Improved metrics derived from the transthoracic impedance (Z) available from implanted Medtronic devices may provide more sensitive indicators of the state of compensation for heart failure patients. Quantification of specific data may provide new information that can improve quality of life for patients and offer vital information to clinicians regarding the adequacy of inpatient and outpatient assessment and management of acute decompensated heart failure.

Enrollment: 11 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with systolic dysfunction
• Able to provide informed consent
• Have a Medtronic manufactured device with Thoracic Impendence Monitoring capabilities

Exclusion criteria

• Patients with severe congestive heart failure who are intubated
• Patients who are oxygen dependent on continuous positive or bilevel positive ventilation
• Inability to tolerate postural variations due to congestive heart failure or other medical or surgical condition.Unable to complete proposed testing
• Subjects who cannot giveWill not give written, informed consent on their own behalf

Trial design

11 participants in 1 patient group

Heart Failure

Description:

Subjects have implanted Medtronic device and a primary diagnosis of left ventricular systolic dysfunction

Treatment:

Device: Medtronic ICDs, CRT-Ds, and CRT-Ps