Earliest Lung Ultrasound Time for Predicting the Need of Surfactant

Gozdem Kayki

Status: Completed

Conditions: Respiratory Distress Syndrome

Treatments: Diagnostic Test: lung ultrasound

Study type: Observational

Funder types: Other

Identifiers

NCT04544514

go 20 334

Details and patient eligibility

About

Lung ultrasonography (LUS) is fast and easy technique. it also has high reliability, so it has started to be used more in evaluating respiratory distress in the neonatal period. The most important feature of LUS is being radiation-free. Three LUS findings that show respiratory distress syndrome were described. They were white lung appearance, lack of preserved areas and loss of pleural integrity. The sensitivity of these findings was found to be 98-100% and the specificity 92-100%. A few studies have shown that surfactant need can be determined by LUS.

It was observed that lung findings were more severe in LUS performed in the early period because of non-completed fetal lung fluid clearence, but the findings could be improved during follow-up. Therefore, it is not known when the earliest time of LUS shows the actual clinical condition and course of the patient.

This study was planned to find the most reliable and earliest US time. Evaluation with LUS was done at 30 minutes and repeated at 1, 2, 4 and 6 hours of life. The LUS findings would be compared with x-ray findings and the correlation of surfactant need with LUS findings would also be investigated.

Enrollment: 71 patients

Sex: All

Ages: 30 minutes to 6 hours old

Volunteers: No Healthy Volunteers

Inclusion criteria

• preterm babies with a gestational age 32 weeks or less
• babies treated with CPAP

Exclusion criteria

• If a baby was intubated in delivery room because of the responsiveness to face-mask ventilation, he/she was excluded.
• congenital heart diseases
• complex congenital malformations
• chromosomal abnormalities.