Early Arthroscopic Partial Meniscectomy(APM)

Yangtze University

Status: Enrolling

Conditions: Meniscus Tear

Treatments: Procedure: early APM; Procedure: delayed APM

Study type: Interventional

Funder types: Other

Identifiers

NCT05114694

APM TIME

Details and patient eligibility

About

Arthroscopic partial meniscectomy(APM) surgery outcomes for Metabolic Syndrome(MetS) patients with degenerative meniscus tears(DMTs) was still not clear. The aim of the study was to investigate outcomes of early APM vs delayed APM for MetS patients with degenerate meniscus tears.

Full description

Degenerate meniscus tears(DMTs) were the most common knee disease in aged and obese people. The most common treatment for DMTs was arthroscopic partial meniscectomy(APM) surgery. However, the time window for performing APM surgery was unclear, especially in obese patients with Metabolic syndrome(MetS). Abdominal obesity, insulin resistance with or without glucose intolerance, dyslipidemia or elevated blood pressure are included in the principal components of MetS. Whether early APM within 3 to 6 months or delayed APM surgery within 6 to 12 months are benefical to MetS patients with DMTs. The knee function outcomes between early APM and delayed APM for MetS patients with DMTs were assessed and follow up to 12 months after surgery.

Enrollment: 120 estimated patients

Sex: All

Ages: 35 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• • Must be age between 35 and 70 years old;

  • Clinical diagnosis of metabolic syndrome;
  • Clinical diagnosis of degnerate meniscus tears;

Exclusion criteria

• Must be able to have no acute knee injury such as car crash or acute sports injury;

  • Must be able to have no knee surgeries history;
  • Must be able to have no rheumatoid arthritis or serious knee osteoarthritis with deformity;
  • Must be able to have no contraindications to MRI;
  • Must be able to have no severe cardiopulmonary disease;
  • Must be able to have no musculoskeletal or neuromuscular impairments ;
  • Must be able to have good visual, hearing, or cognitive;

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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120 participants in 2 patient groups, including a placebo group

early APM

Experimental group

Description:

Early APM group were patients have knee syndrome within 3 to 6 months

Treatment:

Procedure: early APM

delayed APM

Placebo Comparator group

Description:

delayed APM group recruit participants who received delayed APM surgery within 6 to 12 months

Treatment:

Procedure: delayed APM