Early Cardiac Extubation After Cardiac Surgery

University of Liege

Status: Unknown

Conditions: Post-operative Cardiac Surgery

Treatments: Procedure: Early extubation

Study type: Observational

Funder types: Other

Identifiers

NCT05050435

Ulganescardio001

Details and patient eligibility

About

The management of heart valve disease is constantly evolving over time. The minimally invasive approach (mini-thoracotomy and J-hemisternotomy) is one of the major surgical evolutions. It has many advantages including, among others, a reduction of postoperative pain and the preservation of sternal stability This evolution of the surgical technique towards a less invasive approach encouraged the investigators to adapt the anesthetic management accordingly. In particular, immediate postoperative extubation appeared feasible. The investigators would therefore like to test the hypothesis that immediate extuation is non-inferior to delayed extubation with regard to patient safety. The investigators also investigated whether immediate extubation could be beneficiel in terms of vasopressors requirement, risk of early postoperative complications, fluid balance and length of stay in the intesive care unit and in the hopsital.

Enrollment: 500 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Minimally invasive valve replacement intervention (thoracotomy or J-hemisternotomy)

Exclusion criteria

• Combined surgery

Trial design

500 participants in 2 patient groups

Early extubated (in operating room) patients after valvular cardiac surgery

Treatment:

Procedure: Early extubation

Later extubated (in ICU) patients after valvular cardiac surgery