Early Detection of Aortic Stenosis in the Community During Flu Vaccination (FluClinic)

Institut für Pharmakologie und Präventive Medizin

Status: Completed

Conditions: Aortic Stenosis

Study type: Observational

Funder types: NETWORK; Industry

Identifiers

NCT03250806

FluClinic

Details and patient eligibility

About

Prospective cohort study to test the hypothesis that patients identified with severe aortic stenosis are under-diagnosed and under-treated. Such patients shall be identified by auscultation or target echocardiography during flu vaccination. The hypothesis is that this will increase detection of aortic stenosis in the community.

Full description

The design plans for two study phases:

1. Feasibility study: screening by auscultation and target echocardiography during flu vaccination in a single practice in Birmingham;
2. Screening study: multi-centre screening by auscultation or target echocardiography in geographically diverse general practices across the United Kingdom.

In each phase, the patient will be identified by auscultation and target echocardiography. Management and onward referral will be at the clinical discretion of the GP. Results of clinical review, investigation, follow-up and management will be recorded at 3 months from that date.

Enrollment: 167 patients

Sex: All

Ages: 65+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adults aged over 65years attending for influenza vaccination.
• written informed consent to data collection

Exclusion criteria

• known aortic stenosis
• previous aortic valve repair/replacement

Trial design

167 participants in 1 patient group

newly identified aortic stenosis

Description:

Patients identified on auscultation or target echocardiography with aortic stenosis. Consecutive patients per centre with no limit to numbers.