Early Detection of Cognitive Dysfunction in Diabetes

Wuhan General Hospital of Guangzhou Military Command

Status: Unknown

Conditions: MCI; DM; Dementia

Study type: Observational

Funder types: Other

Identifiers

NCT01830998

20130401

Details and patient eligibility

About

The rate of cognitive decline due to ageing is increased 1.5-fold to 2.0-fold in individuals with type 2 diabetes.There are no established specific treatment measures to prevent or ameliorate cognitive impairments in patients with diabetes. we want to detecte early clinical dementia in diabete.

Full description

Clinically relevant cognitive decrements in relation to diabetes mainly occur during two crucial periods in life: the period of brain development in childhood, and the period when the brain undergoes neurodegenerative changes associated with ageing.Potential leads for treatment are to optimise glycaemic control and avoid and treat vascular risk factors.we want to detecte early clinical dementia in diabete by MMSE and Olfactory function.

Enrollment: 400 estimated patients

Sex: All

Ages: 50 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients with type 2 diabetes(Age>50 years)

Exclusion criteria

• with stroke or other complications.

Trial design

400 participants in 4 patient groups

control,MCI, Olfactory dsfunction

Description:

There are different groups:control,MCI, Olfactory dsfunction.

control, MCI

Description:

control and MCI group.Glycaemic control

control and MCI

Description:

treatment and without treatment

MCI and Olfactory function

Description:

observation between MCI and Olfactory function groups.