Early Detection of Head and Neck Superficial Squamous Cell Carcinoma in Patients With Esophagus Squamous Cell Carcinoma

Shandong University

Status

Unknown

Conditions

Optical Enhancement Endoscopy

Treatments

Device: first WLI

Device: first OE

Study type

Interventional

Funder types

Other

Identifiers

NCT03700398

2017SDU-QILU-06

Details and patient eligibility

About

the investigators randomly divide the eligible objects into two groups:1. objects in this group will first receive OE endoscopy observation and subsequent white light imaging(WLI) observation during oropharynx and hypopharynx; 2. objects in this group will first receive WLI observation and subsequent OE observation during oropharynx and hypopharynx. Then, the investigators will compare the detect rate of oropharyngeal and hypopharyngeal superficial squamous cell carcinoma of two groups to find if OE endoscopy can improve the detect rate of oropharyngeal and hypopharyngeal superficial squamous cell carcinoma in esophageal cancer patients.

Enrollment

214 estimated patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

order than 18 years old
Previous or current histopathological pathology confirmed the presence of esophageal squamous cell carcinoma

Exclusion criteria

Previously confirmed pharynx/oropharyngeal squamous cell carcinoma
Advanced pharynx/hypopharyngeal squamous cell carcinoma
Pregnant women and lactating women
pharyngeal or esophageal stenosis, esophageal varices, or active digestive tract hemorrhage influence the observation or fail to obtain pathological diagnosis
Previous chemotherapy or radiation therapy affected observation
Not completed gastroscopy or refused to take biopsy for various reasons
Mental illnesses such as anxiety and depression affect the endoscopic observation
Severe systemic disease, can not tolerate gastroscopy
Refusal to sign informed consent books