Early Detection of Vaping-related Vascular Diseases (ENDS)

University of Miami

Status: Enrolling

Conditions: Blood Vessel Injury; Vaping

Study type: Observational

Funder types: Other

Identifiers

NCT05454267

20211060

Details and patient eligibility

About

The purpose of this study is to determine how vaping affects blood vessels, in particular if early damage occurs in the lung vessels.

Enrollment: 90 estimated patients

Sex: All

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

Vapers Group:

1. Current electronic cigarette (EC) Puff Bar users defined as using EC either daily or occasionally in the past 30 days for at least 6 months, and with 5% nicotine concentration pods.
2. Adults aged 18-40 years

Healthy Group:

1. Healthy never smokers, never vapers
2. Adults aged 18-40 years

Exclusion criteria

1. Current or past smoking of tobacco cigarette (TC) or other tobacco/nicotine products (e.g., smokeless tobacco, Hookah) or marijuana will be excluded from the study.
2. Subjects with self-reported history of chronic health problems including asthma, chronic obstructive pulmonary disease (COPD), morbid obesity (BMI>40 kg/m2), hypertension or diabetes
3. Pregnant or breastfeeding women

Trial design

90 participants in 3 patient groups

Healthy Volunteer Group

Description:

Participants who have never smoked or vaped

High Frequency Vaping Group

Description:

Participants who vape \>20 days per month.

Low-Frequency Vaping Group

Description:

Participants who vape \< 20 days per month