Early Diagnosis for Ocular Ischemia Syndrome Using Arterial Spin Labeling Magnetic Resonance Imaging Technique

Capital Medical University

Status

Unknown

Conditions

Ocular Ischemia Syndrome

Treatments

Diagnostic Test: Fundus fluorescein angiography

Diagnostic Test: Arterial spin labeling (ASL) magnetic resonance imaging

Study type

Observational

Funder types

Other

Identifiers

2018-P2-185-02

Details and patient eligibility

About

To evaluate ocular blood perfusion status and the possibility of craniocerebral vascular lesions of patients with ocular ischemia syndrome (OIS) using arterial spin labeling (ASL) magnetic resonance imaging technique.
To evaluate the specificity, sensitivity and accuracy of arterial spin labeling (ASL) magnetic resonance imaging technique in OIS diagnosis, compared with the traditional routine examination method.

Enrollment

190 estimated patients

Sex

All

Ages

50 to 80 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Ocular ischemia syndrome group: Patients diagnosed with ocular ischemia syndrome;
Age-related macular degeneration group (Control group): Patients diagnosed with age-related macular degeneration;
Age: 50-80 years;
Sex: all;
Patients signed written informed consent.

Exclusion criteria

Fundus fluorescein angiography (FFA) clear images cannot be obtained due to refractive media problems(such as corneal leukoplakia, severe cataract, vitreous hemorrhage, etc.) ;
Patients with contraindications for FFA;
Patients was unable to perform magnetic resonance rmaging (MRI) test;
Patients with history of bleeding and cerebral infarction;
Patients with a history of surgery within 3 months;
Patients who had participated in other clinical trials within 3 months;
Patients who disagree and refuse to participate in the trial.