Early Diagnosis of Acute Renal Failure by Urine Trehalase Levels.

Istinye University

Status: Not yet enrolling

Conditions: Trehalase Levels; Acute Kidney Injury

Treatments: Diagnostic Test: trehalase levels

Study type: Observational

Funder types: Other

Identifiers

NCT06505655

istinye university trehalase

Details and patient eligibility

About

We think that in surgical patients requiring hypotensive anesthesia, acute kidney injury, which may occur due to intraoperative renal hypoperfusion, can be diagnosed early by evaluating the urine trehalase value using the ELISA method, and thus, early diagnosed acute renal failure can be treated quickly and patients can be protected from subsequent complications in the postoperative period.

Enrollment: 40 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Being over the age of 18 and under the age of 65
• Having signed the BGOF form to be included in the study,
• Being in ASA 1 or ASA 2 classification
• Not having kidney failure or kidney disease
• No history of single kidney or renal transplantation
• Not using nephrotoxic drugs or agents before surgery
• Renal function tests taken preoperatively should be within normal ranges.
• No urinary tract infection or urinary problems (such as polyuria, oliguria or anuria)

Exclusion criteria

• Those under the age of 18 or over the age of 65
• Those who do not want to participate in the study
• ASA 3 and above
• Having previously received treatment for kidney disease - including kidney stones -
• Having been previously diagnosed with acute or chronic renal failure
• Having a single kidney or a history of renal transplantation
• Using nephrotoxic drugs or agents (such as contrast material) before surgery
• Kidney function tests taken preoperatively are not within normal ranges
• Having a urinary tract infection or urinary problem (such as polyuria, oliguria or anuria)
• Having a history of kidney stones, acute renal failure or chronic renal failure
• Those with active infection or disease before surgery
• They were determined as patients for whom consent was not obtained for the study.