Early Evaluation of Left Ventricular Systolic Function Impairment in Patients With Chronic Kidney Disease by Multimodal Ultrasonography

Fifth Affiliated Hospital, Sun Yat-Sen University

Status: Enrolling

Conditions: Chronic Kidney Diseases; Left Ventricular Systolic Dysfunction

Study type: Observational

Funder types: Other

Identifiers

NCT06221891

ZDWY.CSK.006

Details and patient eligibility

About

The goal of this observational study is to learn about the value of multimodal ultrasound in early detection of left ventricular systolic dysfunction in patients with chronic kidney disease(CKD). The main questions it aims to answer are:

1. If first-phase ejection fraction（EF1）could early detect the left ventricular systolic dysfunction in patients with CKD.
2. Whether EF1 can detect left ventricular systolic dysfunction in patients with CKD more sensitively than speckle-tracking echocardiography and myocardial work.

Participants will need to cooperate to do an echocardiography. Researchers will compare healthy volunteers and patients with CKD to see if EF1 could early detect the left ventricular systolic dysfunction.

Enrollment: 500 estimated patients

Sex: All

Ages: 18 to 75 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients with chronic kidney disease who are hospitalized in The Fifth Affiliated Hospital of Sun Yat-sen University.
• LVEF≥50%.

Exclusion criteria

• Patients with primary hypertension, diabetes and congenital heart disease.
• Patients who are pregnant or lactating.
• Patients with the blurry ultrasound images.

Trial design

500 participants in 2 patient groups

case group

Description:

This group contains the patients with chronic kidney disease.

control group

Description:

This group contains the healthy adults.