Early Goal-Directed Therapy Utilizing Transpulmonary Thermodilution and Severe Burn Injury

Chang Gung Medical Foundation

Status: Completed

Conditions: Burns

Treatments: Other: Study group: TPTD device was implemented for monitoring.; Other: Control group: Patients being admitted when The advancement of transpulmonary thermodilution(TPTD) device was unavailable.

Study type: Observational

Funder types: Other

Identifiers

NCT05420610

202101364B0

Details and patient eligibility

About

This study aimed to optimize fluid resuscitation with transpulmonary thermodilution (TPTD)-guided protocol and to lower the mortality rate of the severely burned.

Enrollment: 66 patients

Sex: All

Ages: 18 to 100 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult patients (age > 18 years).
• Major burn (as total burned surface area (TBSA) > 20% with at least second degree burn depth).
• Admitted to the intensive care unit (ICU) of the Burn Center.

Exclusion criteria

• Patients younger than 18 years old.
• Patients with severe cardiopulmonary diseases, or associated with other major trauma.
• Patient with incomplete data.

Trial design

66 participants in 1 patient group

Patients with major burn.

Description:

Adult patients (age \> 18 years) suffered from major burn which defined as total burned surface area (TBSA) \> 20% with at least second degree burn depth were admitted to the intensive care unit (ICU) of the Burn Center at a tertiary medical center were retrospectively reviewed.

Treatment:

Other: Study group: TPTD device was implemented for monitoring.

Other: Control group: Patients being admitted when The advancement of transpulmonary thermodilution(TPTD) device was unavailable.