Early Markers of Radiation-Induced Cardiac Injury in Hodgkin Lymphoma Treated With Radiation Therapy

University of Florida

Status: Completed

Conditions: Hodgkin's Lymphoma

Treatments: Procedure: Echocardiogram; Procedure: Cardiac Magnetic Resonance Imaging

Study type: Observational

Funder types: Other

Identifiers

NCT02404818

IRB201703302 (Other Identifier)

UFPTI-1431-HL02

Details and patient eligibility

About

The purpose of this study is to evaluate if radiation and chemotherapy treatment cause cardiac abnormalities among survivors of Hodgkin's lymphoma.

Enrollment: 5 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Completed radiation and chemotherapy treatment for Hodgkin lymphoma involving the mediastinum.
• Patient must be ≥ 18 years at time of consent.

Exclusion criteria

• Pregnant women at time of Cardiac MRI
• Contraindications to Cardiac MRI (contrast allergy, metal implants, medical devices)
• Glomerular filtration rate (GFR) < 30, unless approved by Radiologist (UF Health Jacksonville Radiology Policy: Administration of Gadolinium-Based Contrast Agents).

Trial design

5 participants in 1 patient group

Survivors of Hodgkin's lymphoma

Description:

Cardiac Magnetic Resonance Imaging and Echocardiogram

Treatment:

Procedure: Echocardiogram

Procedure: Cardiac Magnetic Resonance Imaging