Early Metabolic Response in Locally Advanced Esophageal Cancer Undergoing Induction Chemoradiotherapy

Universitaire Ziekenhuizen KU Leuven

Status: Completed

Conditions: Esophageal Carcinoma (Squamous Cell Carcinoma - Adenocarcinoma)

Treatments: Other: 18-FDG-PET-CT

Study type: Observational

Funder types: Other

Identifiers

NCT01269970

S24640 (Registry Identifier)

G.0175.03

Details and patient eligibility

About

Early metabolic response evaluation may predict clinical and histopathological response after neoadjuvant chemotherapy. Its value in neoadjuvant chemoradiotherapy (CRT) is unknown. Our aim was to assess the value of early metabolic response after one cycle of chemotherapy using 18-FDG-PET-CT to predict pathological response and outcome in cT2-4 N0/+ esophageal cancer treated by neoadjuvant CRT and esophagectomy.

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• locally advanced esophageal cancer (cT2-4 N0/+)

Exclusion criteria

• PET-CT not performed at UZLeuven
• Other tumor types
• Distant metastases (organ)

Trial design

0 participants in 1 patient group

locally advanced esophageal carcinoma (cT2-3N0/+)

Treatment:

Other: 18-FDG-PET-CT