Early Outpatient Hysteroscopy Can Prevent Intrauterine Adhesion After Induced Abortion

Chang Gung Medical Foundation

Status: Completed

Conditions: Hysteroscopy; Intrauterine Adhesion

Treatments: Procedure: Hysteroscopy

Study type: Interventional

Funder types: Other

Identifiers

NCT04166500

CMRPG8J1131

Details and patient eligibility

About

Background: Intrauterine adhesions are a difficult clinical problem for reproductive infertility. The most common cause is uterine cavity surgery and post-abortion (including abortion and spontaneous abortion). After the abortion, the uterine cavity adhesion, when is the key point, the literature is not much ink, early literature has mentioned that after the abortion, the uterus scraping action is scraped in four days and the uterine adhesion will be smaller than one to four weeks. Much more, it seems that the sooner the uterine adhesion factor is excluded, the more it can reduce uterine adhesion, but the uterine curettage itself is a risk factor for uterine adhesion. This early practice, the current clinical application, is not used, Instead, it is a hysteroscopy. Our past clinical observations, as soon as possible after the abortion, outpatient hysteroscopy, can find the tissue factors that may cause adhesion in the uterine cavity as soon as possible, and immediately remove it with an outpatient hysteroscope.

Objective: To verify the early outpatient hysteroscopy and reduce the occurrence of intrauterine adhesion after abortion.

Expected benefits to patients: Abortion is likely to cause intrauterine adhesions, which may further cause the incidence of reproductive infertility, should be involved before the formation of permanent injury, reduce the adhesion of the uterine cavity. Outpatient hysteroscopy is a simple and easy-to-use examination procedure that is painless and does not require anesthesia. Although it is invasive but has few complications, it is expected to reduce the occurrence of intrauterine adhesion after abortion.

Enrollment: 70 patients

Sex: Female

Ages: 20 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• female age 20 to 45 years-old
• undergo induced abortion
• desire future fertility
• agree with the trial and sign the consent form

Exclusion criteria

• previous intrauterine surgery
• previous intrauterine adhesion
• previous having over(and/or equal to) 3 times of induced abortion
• infection condition

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

---

70 participants in 2 patient groups

Intervention

Experimental group

Treatment:

Procedure: Hysteroscopy

Control

No Intervention group