Early Prediction of Postpartum Glucose Metabolism Abnormalities in Gestational Diabetes Mellitus

Women's Hospital School Of Medicine Zhejiang University

Status

Enrolling

Conditions

Gestational Diabetes Mellitus

Treatments

Other: Questionnaire survey and specimen collection

Study type

Observational

Funder types

Other

Identifiers

NCT05670548

IRB-20220336-R

Details and patient eligibility

About

This project is expected to screen reliable serum markers in pregnant women with gestational diabetes mellitus (GDM) by using metabolic profiling and lipid profiling clinical high-throughput mass spectrometry technology. We intend to build an early pregnancy prediction model for postpartum glucose metabolism abnormalities of GDM. At the same time, this project plans to develop a predictive management system based on this model, so that it can be widely used in clinical detection process, realize the advance of the early warning window period of abnormal glucose metabolism, and provide theoretical guidance for the early postpartum blocking of GDM to the outcome of abnormal glucose metabolism.

Enrollment

2,000 estimated patients

Sex

Female

Ages

20 to 49 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Plan to have routine prenatal examinations and give birth in the research center
GDM was diagnosed at 24-28 gestational weeks
Singleton pregnancy
Without other pregnancy complications
Willing to cooperate with the hospital to follow up

Exclusion criteria

Have diseases that affect metabolic function or even threaten the life of the mother and fetus before pregnancy, such as diabetes, heart disease, liver and kidney diseases, thyroid diseases with drug, autoimmune diseases, malignant tumors, AIDS, etc.
Fetus has a known deformity or genetic defects
Incomplete clinical data