Early Renal Replacement Therapy in COVID 19 Patients With AKI Does it Improve the Outcome?

Sohag University

Status: Completed

Conditions: Multi Organ Failure

Treatments: Procedure: haemodialysis

Study type: Interventional

Funder types: Other

Identifiers

NCT05274685

soh-Med-22-2-24

Details and patient eligibility

About

patients will be divided into two equal groups, each group including 50 adult patients with a confirmed diagnosis of covid, patients with acute kidney injury, the first group will be treated with early hemodialysis, second group will be conservative until there is an urgent need for dialysis

Enrollment: 100 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• adult patients (≥18 years old) with confirmed severe acute respiratory syndrome coronavirus 2 infections admitted to the ICU.

Exclusion criteria

• •Malignancy.

  • Immuno-deficiency diseases.
  • Chronic diabetic, cardiac and hypertensive patients
  • autoimmune diseases.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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100 participants in 2 patient groups

covid positive with acute kidney injury receiving early renal replacement

Experimental group

Treatment:

Procedure: haemodialysis

covid positive with acute kidney injury under conservative management

Experimental group

Treatment:

Procedure: haemodialysis