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Early Revalvulation After Fallot Repair Improves Clinical Outcome

U

Universitaire Ziekenhuizen KU Leuven

Status

Completed

Conditions

Tetralogy of Fallot

Treatments

Other: Revalvulation

Study type

Observational

Funder types

Other

Identifiers

Details and patient eligibility

About

Aim With this retrospective study, the investigators would like to evaluate and, if possible confirm, whether earlier revalvulation of the right ventricular outflow tract is better than late revalvulation. Up to now, no analysis is done to validate this policy change.

Patient selection All patients registered in the database of paediatric and congenital cardiology of the University Hospitals in Leuven, with sufficient follow-up data, and who underwent transannular patching at repair will be included in the study.

Methodology and statistical analysis All files will be reviewed for demographic, electrocardiographic, echocardiographic, and outcome data. Besides descriptive statistics, Cox regression will be performed to detect whether the time period between repair and revalvulation influences clinical outcome (defined as death, heart failure hospitalization, redo-revalvulation, implantation of automatic defibrillator, endocarditis).

Enrollment

320 patients

Sex

All

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Tetralogy of Fallot patients repaired with transannulaire patch.

Exclusion criteria

  • None.

Trial design

320 participants in 2 patient groups

Revalvulation time early
Description:
Early revalvulation by homograft or percutaneous valve
Treatment:
Other: Revalvulation
Revalvulation time late
Description:
Late revalvulation by homograft or percutaneous valve
Treatment:
Other: Revalvulation

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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