Early Treatment Based Neuroscience Education in Knee (ETbNE)

University of Malaga

Status: Begins enrollment in 8 months

Conditions: Anterior Cruciate Ligament Injuries; Anterior Cruciate Ligament Rupture

Treatments: Other: Best current rehabilitation protocol; Other: Cross-training protocol

Study type: Interventional

Funder types: Other

Identifiers

NCT05440890

UMAESHPhD

Details and patient eligibility

About

Determine the effecttiveness of a cross-education strength training protocol in a group of subjects with an anterior cruciate ligament surgery.

Full description

The cross-education (CE) phenomenon has been studied in recent years as a form of gain muscle strength not only in healthy subjects but also in acute injuries such as musculoskeletal disorders and immovilitations. Unilateral training of the not injured limb has been suggested as an option to produce cross-edutation in terms of strength and skills. In addition, functional magnetic resonance imaging have been postulated as a promising tool to study the mechanisms of transfer.

In the context of our study, arthrogenic muscle inhibition (AMI) of knee extensors is a common consequence after ACL repair in which a CE strength training can lead to reduce quadriceps atrophy and its implications in long terms achievements. Thus, an unilateral strength protocol of the uninjuried limb, according to the last Delphi Consensus, will be run for 8 weeks to check the possible benefits of the transfer in a sample of ACL repair.

Enrollment: 45 estimated patients

Sex: All

Ages: 18 to 40 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• People between 18 and 40 years whith MRI diagnosis of ACL rupture.
• Autograft, allograft or artificail graft of any source.
• With/without any meniscal resection/repair.

Exclusion criteria

• Diagnosis of systematic disease, no injury or symptomatic in contralateral lower limb, pregnancy, current or prior neurologic condiction.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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45 participants in 2 patient groups

Control group

Active Comparator group

Description:

Standard protocol rehabilitation programme for an anterior cruciate ligament repair based on VAN MELICK N, et al 2016.

Treatment:

Other: Best current rehabilitation protocol

Cross-education group

Experimental group

Description:

Standard protocol rehabilitation programme for an anterior cruciate ligament repair based on VAN MELICK N, et al 2016. Additionally a contralateral lower limb strength training.

Treatment:

Other: Cross-training protocol

Other: Best current rehabilitation protocol