Early vs. Late Tracheostomy in Patients With Guillain -Barre Syndrome

Clalit Health Services

Status: Enrolling

Conditions: Guillain Barre Syndrome; Mechanical Ventilation

Treatments: Procedure: Late tracheostomy (more than 7 days from intubation); Procedure: early tracheostomy (less than 7 days from intubation)

Study type: Observational

Funder types: Other

Identifiers

NCT06612242

0206-24-MMC

Details and patient eligibility

About

Tracheostomy is one of the most common procedures in the intensive care unit in patients who need prolonged invasive mechanical ventilation. There is controversy in the literature regarding the ideal timing for performing tracheostomy in critically ill patients. Early tracheostomy may be associated with a decrease in ventilation days and hospitalization. We would like to investigate whether in ventilated patients with Guillain Barre syndrome, early tracheostomy will be associated with decreased ventilation days, decreased mortality and shorter hospital and ICU length of stay.

Enrollment: 30 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria: All patients aged 18--99 who were admitted to the general intensive care unit from January 2012 to September 2024 with a diagnosis of Guillain-Barre syndrome who required mechanical ventilation and underwent tracheostomy during ICU stay.

Exclusion Criteria: Missing recoreded data

Trial design

30 participants in 2 patient groups

Early tracheostomy

Description:

Patients with Guillain Barre who underwent early tracheostomy

Treatment:

Procedure: early tracheostomy (less than 7 days from intubation)

Late tracheostomy

Description:

Patients with Guillain Barre who underwent late tracheostomy

Treatment:

Procedure: Late tracheostomy (more than 7 days from intubation)