Early Waning of Maternal Measles and Meningitis C Antibodies (EWMM)

Guangzhou Center for Disease Control and Prevention

Status

Unknown

Conditions

Measles

Study type

Observational

Funder types

Other

Identifiers

NCT02219061

GZCDC001

Details and patient eligibility

About

Maternal antibodies (measles and meningitis C) may wane in the first six months after birth.

Geometric mean titers(GMTs) of measles and meningitis C.
Follow-up on 0 month, 3rd month,5th month and 7th month after birth.

Full description

Measles and meningitis C are hot topics in China in recent years. Although China had set the goal of measles elimination, many measles cases were found to be those aged < 8 months and meningitis C is becoming public health issue since meningitis group A has been controlled at a very low level and little is known on C group. So the investigators designed the observation study on the two antibodies.

Maternal antibodies are supposed to wane after birth. Serums of the placenta(0 month), children of 3 months, 5 months and 7 months old will be collected and the geometric mean titers (GMTs) of measles and meningitis C will be confirmed by using the ELISA test.

Enrollment

100 estimated patients

Sex

All

Ages

Under 7 months old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria