Eating With Eosinophilic Esophagitis (EoE)

Mayo Clinic

Status: Completed

Conditions: Eosinophilic Esophagitis (EoE)

Treatments: Behavioral: Observed eating session

Study type: Observational

Funder types: Other

Identifiers

NCT03581838

18-002628

Details and patient eligibility

About

Is there a difference in the eating process for patients with active Eosinophilic Esophagitis (EoE) and those with inactive disease?

Full description

Eosinophilic esophagitis (EoE) patients develop adapted eating behaviors to prevent symptoms. These patients tend to cut their food small, chew extensively, take copious liquids with meals, and avoid foods that cause symptoms. No studies to date have directly evaluated these eating behaviors in patients with EoE with observation. Furthermore, none of the investigators' current metrics for patient symptom assessment visually evaluate the eating process nor are they compared before and after treatment. As a result, it is unclear if a patient's subjective perception of their eating difficulties and improvement matches with objective measures.

Enrollment: 31 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• 18 years of age and older
• Patients suspected to have Eosinophilic Esophagitis
• Patients being treated for EoE with PPI or a steriod
• EoE patients that are in remission by having less than 22 on the EEsAI questionnaire
• Controls, patients that do not have EoE or other swallowing issues

Exclusion criteria

• Clinical evidence of infectious process potentially contributing to dysphagia (candidiasis, CMV,herpes)
• Other cause of dysphagia identified at endoscopy (reflux esophagitis, stricture, web, ring, achalasia, esophageal neoplasm)
• EoE patients that do not eat sandwiches or feel they could not eat a sandwich.

Trial design

31 participants in 3 patient groups

Acitve EoE

Description:

Observed eating session of Jimmy John's turkey or vegetarian sandwich with water among individuals who have EoE who have not been treated or have not achieved remission from treatment.

Treatment:

Behavioral: Observed eating session

Remission EoE

Description:

Observed eating session of Jimmy John's turkey or vegetarian sandwich with water among individuals who have EoE who are have achieved remission from treatment.

Treatment:

Behavioral: Observed eating session

Controls

Description:

Observed eating session of Jimmy John's turkey or vegetarian sandwich with water among individuals without EoE.

Treatment:

Behavioral: Observed eating session