EBD RCT Trial in Living Donor Liver Transplantation
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About
This study was designed to demonstrate incidence of biliary complication rates after living donor liver transplantation according to the implantation of external biliary drainage throug duct-to-duct anastomosis site.
Full description
Biliary complication is the most common complications after liver transplantation, and it happens more often after living donor liver transplantation (LDLT) than deceased donor liver transplantation.
Many transplant centers adopted their own methods to improve biliary complications after LDLT. One suggested method is the application of external biliary drainage (EBD).
A prospective study was planned to demonstrate effect of EBD on biliary complication after LDLT. Patients who underwent LDLT with duct-to-duct anastomosis will be randomly assinged to application of EBD or conventional duct-to-duct anastomosis without EBD according to a computer generated randomization sequence and allocated in a 1:1 ratio to one of two groups.
Primary outcome is biliary complication incidence 1 year after LDLT.
Enrollment
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Inclusion criteria
- Living donor liver transplantation
- Adult patient (>=18 years old)
- Patients who are available for at least 3 year follow-up after LDLT
Exclusion criteria
- Patients requring hepaticojejunostomy due to anatomical factor or underlying disease
- Re-transplantation
- Multiorgan transplantation
- Emergency transplantation
Trial design
Primary purpose
Allocation
Interventional model
Masking
124 participants in 2 patient groups
Trial contacts and locations
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Central trial contact
Su young Hong, MD
Data sourced from clinicaltrials.gov
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