EBUS-guided TBNA for Molecular Diagnostic of Mediastinal Lymph Nodes (LN)

Heidelberg University

Status: Unknown

Conditions: Non Small Cell Lung Cancer

Treatments: Procedure: EBUS_TBNA

Study type: Observational

Funder types: Other

Identifiers

NCT00982605

MK01

Details and patient eligibility

About

The purpose of this study is to perform molecular diagnostic in mediastinal lymph nodes of non-small cell lung cancer patients sampled by endobronchial ultrasound guided finde needle aspiration (EBUS-TBNA).

Full description

NSCLC is a common cancer. Accurate and early staging has a significant impact on outcome. EBUS-TBNA of involved mediastinal lymph nodes is critical. Molecular markers could improve mediastinal staging.

Enrollment: 50 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age ≥ 18 years
• Samples are collected before surgery or before any therapy
• ECOG 0 or 1
• Clinical stage I-II, T1-2, N0-1, M0)
• Surgically respectable
• Patient with enlarged med. lymphnodes (control group)

Exclusion criteria

• Previous RT/CHT
• Previous or current cancer of other entity

Trial design

50 participants in 1 patient group

non small cell lung cancer

Description:

cancer patients

Treatment:

Procedure: EBUS_TBNA