Echocardiography During Ajmaline Test

Universitair Ziekenhuis Brussel

Status: Unknown

Conditions: Brugada Syndrome

Treatments: Drug: Ajmaline test

Study type: Observational

Funder types: Other

Identifiers

NCT03491475

UniverstairZB

Details and patient eligibility

About

In this study the investigators analyse echocardiographic images before and during Ajmaline test. The purpose is to know if any echocardiographic modifications are present during either negative or positive Ajmaline testing.

Full description

The diagnosis of Brugada Syndrome is made when a type 1 pattern is present on the electrocardiogram (ECG), either spontaneously or after administration of a sodium channel blocker. For pathofysiological understanding, the investigators will analyse echocardiography images before and during the administration of Ajmaline. Comparing echocardiographies before and during negative Ajmaline test, will allow the investigators to indentify the effect of Ajmaline administration on cardiac function. The comparison between images of negative and positive Ajmaline tests will expose differences related to the occurence of a type 1 ECG.

Enrollment: 100 estimated patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• >17 years old
• clinical indication for Ajmaline test

Exclusion criteria

• History of right ventricular outflow tract ablation

Trial design

100 participants in 2 patient groups

Negative Ajmaline test

Description:

No appearance of a type 1 ECG during Ajmaline test

Treatment:

Drug: Ajmaline test

Positive Ajmaline test

Description:

Appearance of a type 1 ECG during Ajmaline test

Treatment:

Drug: Ajmaline test