ECMELLA vs. ECMO on 30-day Mortality

Charité University Medicine Berlin

Status: Unknown

Conditions: Extracorporeal Membrane Oxygenation Complication; Cardiopulmonary Arrest; Acute Myocardial Infarction; Cardiogenic Shock; Cardiac Arrest

Treatments: Device: ECMELLA; Device: VA-ECMO

Study type: Observational

Funder types: Other

Identifiers

NCT05175898

ECMELLA vs. ECMO

Details and patient eligibility

About

This international, multicenter cohort study aims to investigate outcomes after treatment with extracorporeal cardiopulmonary resuscitation (eCPR) during cardiac arrest.

Full description

Left ventricular unloading with Impella® micro-axial pump has been shown to improve survival in patients with cardiogenic shock treated with veno-arterial extracorporeal membrane oxygenation (VA-ECMO). This study aims to investigate whether treatment with VA-ECMO and Impella ® (so called "ECMELLA") during extracorporeal cardiopulmonary resuscitation is associated with improved outcomes.

Enrollment: 60 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult patients
• Cardiac arrest
• Treatment with veno-arterial extracorporeal membrane oxygenation (VA-ECMO) or "ECMELLA" (that is VA-ECMO plus left ventricular Impella® micro-axial pump)

Exclusion criteria

• Non-adult patients
• No treatment with VA-ECMO or "ECMELLA"

Trial design

60 participants in 2 patient groups

VA-ECMO

Description:

Patients who were treated with veno-arterial extracorporeal membrane oxygenation (VA-ECMO) during cardiac arrest.

Treatment:

Device: VA-ECMO

ECMELLA

Description:

Patients who were treated with veno-arterial extracorporeal membrane oxygenation (VA-ECMO) and Impella® micro-axial pump.

Treatment:

Device: ECMELLA