ED Lung Protective Ventilation to Reduce Complications

The Washington University

Status: Completed

Conditions: Ventilator-associated Conditions; Mechanical Ventilation; ARDS

Treatments: Procedure: lung protective ventilation

Study type: Observational

Funder types: Other

Identifiers

NCT02543554

201409024

Details and patient eligibility

About

Early mechanical ventilation, if delivered with injurious settings, can lead to pulmonary complications, such as acute respiratory distress syndrome (ARDS). Mechanical ventilation in the emergency department (ED) has been studied infrequently when compared to the intensive care unit; however, data suggests that ED-based mechanical ventilation has significant room for improvement and may also be a causative factor in ARDS incidence.

Full description

This is a before-after study examining the impact of implementing lung protective ventilation in the emergency department.

Enrollment: 1,705 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• mechanically ventilated via an endotracheal tube in the ED

Exclusion criteria

• death in the ED,
• death or discontinuation of ventilation within 24 hours,
• chronic mechanical ventilation,
• ARDS while in the ED
• transfer to another hospital.

Trial design

1,705 participants in 2 patient groups

Pre-intervention group

Description:

mechanically ventilated patients before implementation of ED lung protective ventilation

Intervention group

Description:

mechanically ventilated patients after implementation of ED lung protective ventilation

Treatment:

Procedure: lung protective ventilation