ED50 of Esketamine for Laser Treatment in Children (ESCALATE)

Air Force Military Medical University of People's Liberation Army

Status: Not yet enrolling

Conditions: Anesthesia

Treatments: Drug: Esketamine

Study type: Interventional

Funder types: Other

Identifiers

NCT06294639

XJA-20240224

Details and patient eligibility

About

There is limited research on the combined use of esketamine and alfentanil for anesthesia during facial laser treatment in pediatric patients, and the effective dosage of esketamine for inhibiting body movement remains unclear. We explore the effective dose of esketamine combined with alfentanil for the inhibition of body movement during facial laser treatment in pediatric patients.

Enrollment: 40 estimated patients

Sex: All

Ages: 3 to 12 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• age between 3 years and 12 years old
• patients scheduled for laser treatment of facial lesion

Exclusion criteria

• patients with airway infection during the last 1 month
• patients with cardiac or pulmonary disorder
• patients with hepatic or renal disfunction
• patients with neurologic or psychiatric disorder

Trial design

Primary purpose: Other

Allocation: N/A

Interventional model: Sequential Assignment

Masking: None (Open label)

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40 participants in 1 patient group

esketamine

Experimental group

Description:

esketamine will be given intravenously

Treatment:

Drug: Esketamine