Edema and Fibrosis CMR Imaging in Cardiomyopathy

University of Pennsylvania

Status: Active, not recruiting

Conditions: Cardiomyopathies

Treatments: Device: 7 T CMR

Study type: Observational

Funder types: Other

Identifiers

NCT03534726

827516

Details and patient eligibility

About

7 Tesla MRI is a new magnetic field strength that has become available at Penn for cardiovascular MRI. This new scanner has potential to improve assessment of cardiovascular disease due to its increased signal-to-noise ratio, higher spatial resolution, and response to magnetic properties of tissue at high field. The purpose of this study is to assess the feasibility of 7 T CMR. Secondly, we wish to investigate its use, to improve clinical and research MRI. Altogether, 7 T may permit better clinical diagnosis of cardiomyopathy.

Enrollment: 13 patients

Sex: All

Ages: 20 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Subjects between the ages of 20-70 years old

Exclusion criteria

• Advanced renal disease (estimated GFR rate < 30 mL/min) or hypersensitivity to gadolinium contrast agent.
• Presence of cardiac pacemaker or implanted cardioverter defibrillator
• Pregnancy
• Inability to provide informed consent
• Other contraindications to MRI (such as claustrophobia)

Trial design

13 participants in 2 patient groups

Patients

Description:

Patients with cardiomyopathy

Treatment:

Device: 7 T CMR

Normal subjects

Description:

No prior history of heart disease.

Treatment:

Device: 7 T CMR