Edessy Stem Cell Score (ESS), Endometrium, Endometrioma

Al-Azhar University

Status: Completed

Conditions: Endometriosis, Ovarian

Treatments: Procedure: Ovarian and endometrial samples

Study type: Interventional

Funder types: Other

Identifiers

NCT02103452

17819555

Details and patient eligibility

About

Purpose of this study is to evaluate stem cell expression (SCE) in endometriotic (E) and non endometriotic ovarian and endometrial tissues.

Full description

This study was conducted on 40 women at Al-Azhar University Hospitals. They are divided into two equal groups, group 1 with ovarian endometrioma and group 2 with normal ovary. Ovarian and endometrial samples were evaluated by hematoxlin & eosin for histopathology (HP) and of oct-4 for immunohistochemistry (IH) for SCE.

Evaluation of IH parameters revealed that the most important factors for evaluating SC were arranged as score ( Edessy Stem Cell Score=ESS).

Enrollment: 80 patients

Sex: Female

Ages: 20 to 40 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 20 to 40 years and did not receive hormonal treatment for three month

Exclusion criteria

• Diabetes mellitus, cardiovascular and kidney diseases, adenomyosis, Uterine fibroid Endometrial carcinoma and Poly cystic ovary

Trial design

Primary purpose: Diagnostic

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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80 participants in 2 patient groups

ovarian endometrioma

Experimental group

Description:

Ovarian and endometrial samples

Treatment:

Procedure: Ovarian and endometrial samples

normal ovary

Experimental group

Description:

Ovarian and endometrial samples

Treatment:

Procedure: Ovarian and endometrial samples