Edible Oils in the Treatment of Constipation of Hemodialysis Patients

Federal University of São Paulo

Status: Completed

Conditions: Chronic Kidney Disease

Treatments: Dietary Supplement: Olive oil; Other: Mineral oil; Dietary Supplement: Flaxseed oil

Study type: Interventional

Funder types: Other

Identifiers

NCT02103556

2012/06605-9

Details and patient eligibility

About

The purpose of this study was to evaluate the effect of olive oil and flaxseed oil in the treatment of constipation of patients undergoing hemodialysis.

Enrollment: 50 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Constipated patients by Rome III criteria
• Hemodialysis > 3 months

Exclusion criteria

• Diagnosis of gastrointestinal disease other than constipation
• Previous intolerance to the oils used in the study
• Cognitive limitations

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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50 participants in 3 patient groups

Mineral oil

Active Comparator group

Description:

4ml daily (adjusted as needed), for 4 weeks

Treatment:

Other: Mineral oil

Olive oil

Active Comparator group

Description:

4ml daily (adjusted as needed), for 4 weeks

Treatment:

Dietary Supplement: Olive oil

Flaxseed oil

Active Comparator group

Description:

4 ml daily (adjusted as needed), for 4 weeks

Treatment:

Dietary Supplement: Flaxseed oil