Eealy Improvement Predicts Antidepressants Response in Adults With Major Depression Disorder

Fudan University

Status: Unknown

Conditions: Major Depressive Disorder

Treatments: Drug: antidepressant

Study type: Observational

Funder types: Other

Identifiers

NCT03230682

KY2017-01

Details and patient eligibility

About

Early improvemrnt, decreased 20% in the 17 items of Hamilton Depression Rating Scale (HAMD-17) at the second week of the treatment of major depression disorder (MDD), can arguably predict the remission at the 12th week. Our observation study including 80 MDD patients will access resting-state function MRI to finding factors which infuencing early improvemrnt, respone and remission of antidepressants.

Enrollment: 80 estimated patients

Sex: All

Ages: 16 to 55 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• right-handed; HAMD-17 more than 17; diagnosed with MDD by the Structured Clinical Interview for DSM-IV

Exclusion criteria

• patients diagnosed with other condition in DSM-IV Axis I; pregnency; Thyroid disease; Heart Disease

Trial design

80 participants in 1 patient group

major depressive disorder

Treatment:

Drug: antidepressant