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Eealy Improvement Predicts Antidepressants Response in Adults With Major Depression Disorder

Fudan University logo

Fudan University

Status

Unknown

Conditions

Major Depressive Disorder

Treatments

Drug: antidepressant

Study type

Observational

Funder types

Other

Identifiers

NCT03230682
KY2017-01

Details and patient eligibility

About

Early improvemrnt, decreased 20% in the 17 items of Hamilton Depression Rating Scale (HAMD-17) at the second week of the treatment of major depression disorder (MDD), can arguably predict the remission at the 12th week. Our observation study including 80 MDD patients will access resting-state function MRI to finding factors which infuencing early improvemrnt, respone and remission of antidepressants.

Enrollment

80 estimated patients

Sex

All

Ages

16 to 55 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • right-handed; HAMD-17 more than 17; diagnosed with MDD by the Structured Clinical Interview for DSM-IV

Exclusion criteria

  • patients diagnosed with other condition in DSM-IV Axis I; pregnency; Thyroid disease; Heart Disease

Trial design

80 participants in 1 patient group

major depressive disorder
Treatment:
Drug: antidepressant

Trial contacts and locations

1

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Central trial contact

Shi Shenxun, PhD

Data sourced from clinicaltrials.gov

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