EEG During Gastroscopy and/or Colonoscopy

Free University of Brussels (ULB)

Status: Enrolling

Conditions: Endoscopy of Stomach (Procedure); Colonoscopy (Procedure); Continuous Processed Electroencephalogram (Procedure)

Treatments: Diagnostic Test: EEG analysis

Study type: Interventional

Funder types: Other

Identifiers

NCT07073274

HUB2025185

Details and patient eligibility

About

During anesthesia, EEG shows specific and significant changes according to the depth of anesthesia and the drugs used. Endoscopic procedures like gastroscopies or colonoscopies are usually done on an outpatient basis using essentially propofol for sedation or anesthesia. Preliminary reports have shown that the depth of anesthesia during these procedures may be very deep resulting even in a burst suppression pattern on the EEG.

In this study, frontal EEG will be recorded continuously using a Root - Sedline device (Masimo, US). Anesthesiologists will be free to use the medications and dosage they judge appropriate. The attending anesthesiologist will be blinded to the EEG. Medications and dosages will be recorded, as well as processed EEG data from the Sedline and the raw EEG. Primary outcome is the % of time spend in specific range of patient state index (PSI 0-10; 10-20; 20-30; 30-40; 40-50; 5-60; 60-70; 70-80; 80-90; 90-100) as well as the % of time spent in burst suppression.

Enrollment: 100 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients undergoing gastroscopy and or colonoscopy in a outpatient setting under sedation or general anesthesia

Exclusion criteria

• Patients < 18 years
• altered renal function, Glomerular filtration rate < 50 mL/min/m2
• altered hepatic tests, > 1.5 * upper normal limit
• Any form of hepatic cirrhosis
• Presence of oesophageal varices
• Any neurological pathology rendering EEG analysis non reliable

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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100 participants in 1 patient group

EEG monitoring

Other group

Description:

Continuous EEG monitoring

Treatment:

Diagnostic Test: EEG analysis