EEG Monitoring for PERFormance Anticipation (MEEGAPERF)

Civil Hospices of Lyon

Status: Completed

Conditions: Healthy

Treatments: Other: Magnetoencephalography (MEG); Other: Production of CO2 (VCO2); Other: Behavioral Measures; Other: Reaction time measurement; Other: Electroencephalography (EEG) multi-sensor; Other: Electrooculogram (EOG); Other: Assessment of physical performance; Other: Consumption of O2 (VO2); Other: Electrodermogram (EDG); Other: Electromyogram (EMG); Other: Electrocardiogram with 3 leads

Study type: Interventional

Funder types: Other

Identifiers

NCT03233282

69HCL16_0661

Details and patient eligibility

About

Identify, characterize and then validate electrophysiological markers linking electrophysiological cerebral activity and performance in cognitive and physical fatigability in humans. To do this, noninvasive explorations of electroencephalography (EEG) and magnetoencephalography (MEG) will be carried out under two conditions of different experiments, the first one that induces a cognitive fatigability and the second one that induces physical fatigability.

Enrollment: 169 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria MGPFco group:

• Adult subjects, male or female, right-handed or left-handed, from 18 years up to 70 years;
• Having duly completed the entire confidential medical questionnaire;
• Written consent of free, informed and express participation;
• No hearing problems;
• Having normal or corrected vision;
• Affiliation to a Social Security scheme.

Inclusion Criteria MGPFph group:

• Adult subjects, male or female, right-handed or left-handed, from 18 years up to 35 years;
• Practicing at least five hours of sports per week;
• Presenting a certificate of no contraindication to an exercise test, intense sports practice or an energy sport in competition of the current year;
• Having duly completed the entire confidential medical questionnaire;
• Without cardiovascular or motor disability;
• Without tumoral, inflammatory, cardiac, pulmonary, renal, digestive (malabsorption syndrome) or liver disease;
• Written consent of free, informed and express participation;
• Affiliation to a Social Security scheme.

Exclusion Criteria:

• Pregnant women, nursing mothers or those of childbearing age without contraception
• Persons under guardianship, curatorship or any other administrative or judicial measure of deprivation of liberty or of liberty
• Persons protected by the law
• Persons who have performed a maximum stress test within 15 days of the date of inclusion,
• In the course of drug treatments against indicated for the protocol (treatment for neurological diseases, psychiatric ...).
• Metal implants incompatible with MRI (for the subjects concerned, see appendices)
• Metallic implants incompatible with the MEG (for the subjects concerned, see appendices)

Trial design

Primary purpose: Basic Science

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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169 participants in 2 patient groups

Cognitive Fatigability

Other group

Treatment:

Other: Electrocardiogram with 3 leads

Other: Electromyogram (EMG)

Other: Electrooculogram (EOG)

Other: Assessment of physical performance

Other: Electroencephalography (EEG) multi-sensor

Other: Reaction time measurement

Other: Behavioral Measures

Other: Magnetoencephalography (MEG)

Physical Fatigability

Other group

Treatment:

Other: Electrocardiogram with 3 leads

Other: Electrodermogram (EDG)

Other: Electromyogram (EMG)

Other: Consumption of O2 (VO2)

Other: Electrooculogram (EOG)

Other: Assessment of physical performance

Other: Electroencephalography (EEG) multi-sensor

Other: Reaction time measurement

Other: Behavioral Measures

Other: Production of CO2 (VCO2)

Other: Magnetoencephalography (MEG)