Nitrous Oxide On Acute Postoperative Pain and Opioid Consumption and Chronic Pain After Inguinal Hernia Repair Surgery

NeuroTherapia, Inc.

Status: Withdrawn

Conditions: Inguinal Hernia Repair; Post Operative Pain

Treatments: Other: oxygen; Drug: Nitrous Oxide

Study type: Interventional

Funder types: Other

Identifiers

NCT01622322

10/1539

Details and patient eligibility

About

To compare postoperative pain, opioid consumption and chronic pain in patients undergoing to hernia repair surgery after receiving nitrous oxide or oxygen during the general anesthesia.

Full description

The study is prospective and double blind. In the clinic, patients undergoing inguinal hernia surgery that meet the criteria for inclusion into the study and agreed to participate in the study will be randomized into two groups. In the first group of patients will receive Nitrous Oxide and In the second group of patients will receive oxygen during the general anesthesia.

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 18 to 65 years old at time of the first procedure
• American Society of Anesthesiologists physical status I or II
• Inguinal hernia repair surgery undergoing the general anesthesia

Exclusion criteria

• Neuropathic disease
• Chronic opioid users
• Contraindication for Nitrous Oxide receive
• Consent will not be obtained patient
• Psychiatric disorders
• Current or recent drug abuse (within past 6 months).

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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0 participants in 2 patient groups, including a placebo group

Nitrous oxide

Experimental group

Description:

Subjects will receive General anesthesia with Nitrous Oxide.

Treatment:

Drug: Nitrous Oxide

Oxygen

Placebo Comparator group

Description:

Subjects will receive General anesthesia with oxygen.

Treatment:

Other: oxygen