Effect of 24 h Severe Energy Restriction on Appetite Regulation and Ad-libitum Energy Intake

Loughborough University

Status

Completed

Conditions

Deficiency; Calorie

Treatments

Other: Energy intake

Study type

Interventional

Funder types

Other

Identifiers

NCT02696772

R13-P149DC

Details and patient eligibility

About

Long term maintenance of weight loss is generally poor, which is at least partly due to increased feelings of hunger associated with restricting what can be eaten. Intermittent severe energy restriction is a novel dietary strategy that requires individuals to consume a very-low energy diet for 1-4 days per week, allowing normal feeding patterns to be adopted on the other days in the week. However, the effect of a consuming a very-low energy diet on appetite regulation, which might represent a key marker of long-term adherence to dieting, has not been determined. This study aimed to assess the effects of severely restricting energy intake for 24 h on markers of appetite regulation, energy balance and metabolism compared to an adequate energy trial.

Enrollment

18 patients

Sex

All

Ages

18 to 50 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

non-smoker, not currently dieting, weight stable for >6 months (self-reported), no known history of cardiovascular or renal disease.

Exclusion criteria

food allergies, dislike or intolerance of study foods and drinks, irregular eating patterns, use of medication that could influence hormone concentrations, excessive alcohol consumption (>4 units/day), intensive training schedule (>10 h/week)