Effect of a Bolus of 10 µg/kg of Alfentanil on the Pupillary Pain Index

Pr Isabelle CONSTANT

Status: Completed

Conditions: Pain; Anesthesia

Treatments: Drug: sevoflurane or propofol; Drug: Alfentanil

Study type: Interventional

Funder types: Other

Identifiers

NCT02646592

PPI Alfentanil

Details and patient eligibility

About

This study aims to assess the Pupillary Pain Index before and after a bolus of alfentanil in children under general anesthesia, before skin incision.

Enrollment: 14 patients

Sex: All

Ages: 2 to 18 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Elective surgery under general anesthesia
• Written informed consent

Exclusion criteria

• Chronic pain
• Preoperative analgesic drug
• Neurologic disease
• Ophtalmic disease

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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14 participants in 1 patient group

alfentanil

Experimental group

Description:

Children under general anesthesia for elective surgery. Induction with sevoflurane or propofol according to the preference of the patient. Maintenance with sevoflurane. 5 minutes before skin incision, first assessment of the pupillary pain index. Then injection of 10 µg/kg of alfentanil. After 5 minutes second assessment of pupillary pain index. End of study period, beginning of surgery.

Treatment:

Drug: sevoflurane or propofol

Drug: Alfentanil