Effect of a Commercial Cosmetic Mouth Rinse on Plaque Re-growth

GlaxoSmithKline (GSK)

Status and phase: Completed; Phase 2

Conditions: Healthy Subjects

Treatments: Drug: 0.12% chlorhexidine mouthrinse; Other: Cosmetic mouthrinse; Other: Sterile water

Study type: Interventional

Funder types: Industry

Identifiers

NCT01122862

Z36420889

Details and patient eligibility

About

A clinical study to evaluate the effect of a commercial mouth rinse on plaque re-growth

Enrollment: 23 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• Good general and oral health
• At least 20 natural gradable teeth
• Mean plaque score (Turesky Modification of the Quigley Hein Index) of greater than or equal to 2.00 at the first baseline visit

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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23 participants in 3 patient groups, including a placebo group

0.12% Chlorhexidine Mouthrinse

Active Comparator group

Description:

Commercially available 0.12% Chlorhexidine mouthrinse

Treatment:

Drug: 0.12% chlorhexidine mouthrinse

Cosmetic mouthrinse

Active Comparator group

Description:

Commercially available cosmetic mouthrinse

Treatment:

Other: Cosmetic mouthrinse

Sterile Water

Placebo Comparator group

Description:

Sterile Water

Treatment:

Other: Sterile water