ClinicalTrials.Veeva

Menu

Effect of a Nickel Free Diet and Nickel Sensitization on GERD Patients.

West Virginia University logo

West Virginia University

Status

Completed

Conditions

Gastroesophageal Reflux

Treatments

Other: Nickel-free diet

Study type

Interventional

Funder types

Other

Identifiers

NCT03720756
1804080531

Details and patient eligibility

About

There is little evidence on the effect of a nickel-free diet on gastroesophageal reflux disease (GERD). We hope to determine if a nickel-free diet improves GERD symptoms in patients with a nickel allergy by having patients complete a questionnaire on their GERD symptoms before and after initiation of 8 weeks on a nickel-free diet.

Enrollment

20 patients

Sex

All

Ages

18+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • age 18 years or older with a history of GERD
  • owns a phone with a camera
  • has access to or is willing to sign up for MyChart
  • is symptomatic for GERD at time of visit as determined by a score of >12 on the GERD Health Related Quality of Life (GERD-HRQL) questionnaire. (Patients that are currently taking a proton pump inhibitor (PPI) they must have been on the PPI for at least 3 months.)

Exclusion criteria

  • less than 18 years of age
  • no not have access to MyChart
  • are not willing to sign up for MyChart
  • have taken an oral steroid within 4 weeks
  • have experienced a sunburn or had significant sun exposure within the last 4 weeks, or applied a topical steroid to the area that the past test will be applied (i.e. upper back or arm) in the last 4 weeks. No vulnerable populations will be included.

Trial design

Primary purpose

Treatment

Allocation

Non-Randomized

Interventional model

Parallel Assignment

Masking

Single Blind

20 participants in 2 patient groups

Subjects WITH nickel-sensitivity
Experimental group
Description:
Subjects on nickel-free diet who have a positive patch-test result, indicating nickel-sensitivity.
Treatment:
Other: Nickel-free diet
Subjects WITHOUT nickel-sensitivity
Active Comparator group
Description:
Subjects on nickel-free diet who have a negative patch-test result, indicating they do NOT have nickel-sensitivity.
Treatment:
Other: Nickel-free diet

Trial contacts and locations

2

Loading...

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2026 Veeva Systems