Effect of a Plant Based Nootropic on Perceptual Decision Making.

University of Leeds

Status: Completed

Conditions: Cognitive Enhancement

Treatments: Dietary Supplement: Placebo; Device: Electroencephalography; Dietary Supplement: Nootropics (ginkgo biloba, nicergoline, piracetam, or others); Behavioral: Perceptual decision-making performance

Study type: Interventional

Funder types: Other

Identifiers

NCT06689644

AUtley

Details and patient eligibility

About

Nootropics are a group of medicinal substances purported to improve important cognitive functions such as learning, focus and memory. Many of these substances have demonstrated beneficial effects on cognitive performance and overall health. However, a thorough understanding of how these substances and their synergistic effects in the form of a supplement may benefit fundamental brain processes is currently lacking. In the current study, we will investigate the effects of a plant-based, nootropic supplement (https://uk.mindlabpro.com/) on perceptual decision-making (i.e. the ability to make rapid decisions based on sensory stimuli) in healthy adult participants.

Full description

Participants will perform a computerised cognitive task assessing their perceptual decision-making pre- and post- 60 days of continuous supplementation with either a plant-based nootropic supplement (Mind Lab pro) or placebo. During testing, electroencephalography (EEG) signals will be captured simultaneously.

Enrollment: 37 patients

Sex: All

Ages: 20 to 59 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Eligibility screening of participants was guided by the following inclusion criteria: (i) be between 20-59 years old, (ii) be right-handed and (iii) be able to cease taking other dietary supplements for two months.

Exclusion criteria

• Exclusion criteria included: (i) currently consuming a nootropic supplement, (ii) any known musculoskeletal, or neurological medical conditions or cognitive impairments (iii) have a known diagnosis of epilepsy/history of seizures and (iv) have a known hearing or visual condition that affects daily life function.

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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37 participants in 2 patient groups, including a placebo group

Experimental group

Experimental group

Description:

This group will receive the nootropic supplement for 60 days.

Treatment:

Behavioral: Perceptual decision-making performance

Dietary Supplement: Nootropics (ginkgo biloba, nicergoline, piracetam, or others)

Device: Electroencephalography

Control group

Placebo Comparator group

Description:

This group will receive a placebo supplement for 60 days

Treatment:

Behavioral: Perceptual decision-making performance

Device: Electroencephalography

Dietary Supplement: Placebo