Effect of a Sequence of Specific Manual Therapy Techniques Targeting the Autonomic Nervous System in Healthy Adults

Universitat Internacional de Catalunya

Status: Enrolling

Conditions: Autonomic Imbalance

Treatments: Procedure: Simulated manual therapy techniques; Procedure: Sequence of manual therapy techniques

Study type: Interventional

Funder types: Other

Identifiers

NCT06477822

FIS-2024-01

Details and patient eligibility

About

The activity of the autonomic nervous system has been shown to influence the appearance of symptoms in some diseases such as rheumatoid arthritis, fibromyalgia, or migraine, among others. In the bibliography we find different authors who, through intervention using manual therapy, have demonstrated its effects on the autonomic nervous system, especially on the increase in parasympathetic activity and reduction in sympathetic activity. A clinical trial is proposed to verify these effects.

Full description

The aim of the study is to analyse the effects of applying a specific sequence of manual therapy techniques focused on the regulation of the autonomic nervous system. This intervention sequence will be applied in a single intervention. As a result, an immediate increase in parasympathetic activity could occur, measured by different parameters of heart rate variability, heart rate and respiratory rate. If the results confirm the expected effects, this treatment sequence could be used as a therapeutic resource in patients with pathologies whose symptoms may be related to the deregulation of the autonomic nervous system, such as rheumatoid arthritis, migraine or fibromyalgia, among others.

Enrollment: 96 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Provision of informed consent
• Aged between 18-65

Exclusion criteria

• Regular consumtion of alcohol or illegal drugs
• Consumption of medications whose effect acts on the autonomic nervous system (cholinergic agonists and antagonists, or adrenergic agonists and antagonists)
• Diagnostic of disease that may affect the activity of the autonomic nervous system or the perception of pain (such as generalized anxiety disorder, fibromyalgia, or chronic fatigue).
• Pregnancy

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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96 participants in 2 patient groups, including a placebo group

Sequence of manual therapy techniques

Experimental group

Description:

Participants receive a manual therapy secuence of techniques

Treatment:

Procedure: Sequence of manual therapy techniques

Simulated manual therapy techniques

Placebo Comparator group

Description:

Participants receive a sequence of simulated manual therapy techniques

Treatment:

Procedure: Simulated manual therapy techniques