Effect of a Specific Blend of Fibers and Probiotics on the Microbiome

Nestlé

Status

Completed

Conditions

Microbiota Perturbation by an Environmental Challenge

Treatments

Dietary Supplement: Fibers and probiotics

Study type

Interventional

Funder types

Industry

Identifiers

19.17.NRC

Details and patient eligibility

About

The study will investigate the effect of a mix of fibers and probiotics on faecal microbiota challenged by an environmental stress

Enrollment

20 patients

Sex

All

Ages

18 to 45 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Exclusion criteria

Known food allergy and intolerance
Currently participating in another clinical trial or research project
Fewer than 5 spontaneous bowel movements per week on average
Chronic or recurrent diarrhea with spontaneous bowel movements more often than 2 times daily
Systemic antibacterial/antifungal therapy during the 3 months prior to study enrolment
Medications or supplements that are known to alter gut function or microflora during the 4 weeks prior to study enrolment
Volunteers under anti-hyperlipidemic, antihypertensive, estrogen-related and/or anticoagulant agents
Prior gastrointestinal surgery (apart from appendectomy, cholecystectomy or herniotomy)
Alcohol intake higher than 2 servings per day. A serving is 0.4 dl of strong alcohols, 1 dl of red or white wine, or 3 dl of beer.
Artificially sweetened beverage intake higher than 1000 ml/ per day
Female subjects will be excluded if they are pregnant, gave birth in the last 6 months, or are lactating.
Subject having a hierarchical or family link with the research team members.