Effect of Açaí Juçara Consumption on Endothelial Function and Arterial Stiffness

Instituto de Cardiologia do Rio Grande do Sul

Status: Unknown

Conditions: Overweight and Obesity

Treatments: Dietary Supplement: Hipocaloric Diet with Açaí Juçara; Other: Hipocaloric Diet

Study type: Interventional

Funder types: Other

Identifiers

NCT04434534

5483/18

Details and patient eligibility

About

This study evaluates the consumption of Açaí Juçara pulp in endothelial function and arterial stiffness in overwheight and obese individuals. Half of participants will receive a hipocaloric diet and two Açaí Juçara pulps for daily consumption, while the other half will receive just a hipocaloric diet.

Full description

Obesity is the most prevalent nutritional disease and a growing public health problem worldwide. This clinical condition is an established risk factor for cardiovascular diseases.

Açaí Juçara is a brazilian fruit, rich in antioxidants, like anthocyanin. This compound have antioxidative and vasodilatory properties. Prospective studies have shown that the antioxidant present in berries can improve vascular health, like endothelial function, measured by Flow Mediated Dilatation (FMD) and arterial stiffness, measured by Pulse Wave Velocity (PWV).

Enrollment: 60 estimated patients

Sex: All

Ages: 30 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Sedentary lifestyle
• Overwheight or obesity "1" diagnostic (BMI >25kg/m² and <35kg/m²)

Exclusion criteria

• Alcoolism
• Smoking
• Diagnostic of Diabetes Mellitus or Coronary Artery Disease
• Use of Statin Therapy
• Cardiovascular diseases
• Infectious Disease

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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60 participants in 2 patient groups

Hipocaloric Diet with Açaí Juçara

Experimental group

Description:

Individualized diet plans calculated for each participant, reducing 500-1000 daily calories, including 200g of Açaí Juçara (2 pulps).

Treatment:

Dietary Supplement: Hipocaloric Diet with Açaí Juçara

Hipocaloric Diet

Active Comparator group

Description:

Individualized diet plans calculated for each participant, reducing 500-1000 daily calories.

Treatment:

Other: Hipocaloric Diet