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Effect of Acitretin Versus Narrowband Ultraviolet B on Neopterin Level in Psoriatic Patients .

S

South Valley University

Status and phase

Unknown
Phase 4

Conditions

Psoriasis

Treatments

Drug: Acitretin 25Mg Cap
Radiation: Narrowband ultraviolet B

Study type

Interventional

Funder types

Other

Identifiers

NCT05401006
209/6/21

Details and patient eligibility

About

To evaluate effect of acitretin versus Narrowband UVB on serum level of neopterin in psoriatic patients.

Enrollment

30 estimated patients

Sex

All

Ages

15 to 60 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Patients with psoriasis diagnosed clinically Aged (15-60).

Exclusion criteria

  • Patient with history of skin cancer.
  • Patient with history of photosensitivity.
  • Pregnancy and lactation.
  • Liver failure.
  • Renal failure.
  • Patient with psoriatic artheritis.
  • Patient with allergy to product or any of its components.
  • Patient with poorly controlled dyslipidemia.
  • Patient receiving tetracyclines.

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Single Blind

30 participants in 3 patient groups

Acitretin
Active Comparator group
Description:
Patients will Receive Acitretin (0.25-1 mg /kg/day )for 3months .
Treatment:
Drug: Acitretin 25Mg Cap
Narrowband ultraviolet B
Active Comparator group
Description:
Patients will receive Narrowband UVB( 3session /week ) for 3months.
Treatment:
Radiation: Narrowband ultraviolet B
Combination of Narrowband ultraviolet B and Acitretin
Active Comparator group
Description:
Patients will receive Acitretin (0.25-1 mg /kg/day ) and Narrowband UVB( 3session /week ) for 3 months.
Treatment:
Radiation: Narrowband ultraviolet B
Drug: Acitretin 25Mg Cap

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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